To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Possibleside effectsareweight gainand suicidal thoughts. Theyll do this by checking certain blood tests. This is not a list of all drugs or health problems that interact with this medicine. This test measures the amount of hemoglobin in your blood. With slow IV injection, the drug is given as a single, slow injection into your vein. Hemoglobin is a protein thats found in your RBCs. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. %PDF-1.3 Or your doctor may recommend that you change your eating habits to include more iron in your diet. Its not known how often people taking a treatment other than Injectafer had diarrhea. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Some people only need one treatment course of Injectafer. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Generics tend to cost less than brand-name drugs. People with IDA have low blood levels of hemoglobin. Below are examples of these side effects. Follow all instructions closely. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. They have been a god send. Here we look at how Injectafer and Venofer are alike and different. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. This hormone is made by your kidneys. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. This is not a complete list of possible side effects. treatment schedule in further detail. (A medication class is a group of medications that work in a similar way.). Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Procedure Details In the second group, some people switched from taking iron by mouth to taking Injectafer. It is important to get each dose of this medication as scheduled. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. If these effects continue or worsen, tell your doctor. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Learn how to store and discard medical supplies safely. These nutrients include iron, vitamin B12, and folate. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Any long-term side effects/dangers from iron infusions? : r/Anemic - Reddit Side effects from HRT depend on a number of factors: This survey is being conducted by the WebMD marketing sciences department. Keep out of reach of children. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Call your doctor for instructions if you miss an appointment for your Venofer injection. other treatments you receive, you will need to go back for several treatments with Venofer. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. (IV iron is absorbed by the body more rapidly than oral iron.) No, Injectafer itself wont make you gain weight. muscle pain. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Risks of Hypophosphatemia Following Intravenous Iron All rights reserved. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. WebMD provides common contraindications for Venofer Vial. For additional information, contact your healthcare provider. Blood tests may be needed to check for unwanted effects. *Patients are calculated based on an estimated annual cumulative dose. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Together, they can recommend ways to help you manage a body weight thats healthy for you. The insurance company will review the prior authorization request and decide if the drug will be covered. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. There are currently no generic forms of either drug. No, you wont need to take iron pills while youre using Injectafer. You may report side effects to the FDA at 1-800-332-1088. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Tell your doctor about the allergy and what signs you had. What are the side effects of Venofer? Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? They can recommend appropriate treatment options. Best food forward: Are algae the future of sustainable nutrition? Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. In the first group, some people continued taking iron by mouth, while other people took Injectafer. If you have questions about side effects, call your doctor. This may lead to the person needing a higher dose compared to someone who is muchsmaller. % Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. If either is present, do not use the liquid. Evenbirth controlcan lead to severeside effectslike bloodclots. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Remember that it is best to get your vitamins and minerals from food whenever possible. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Call your doctor for medical advice about side effects. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Do not exceed 1,500 mg of iron per dosing course. Then the study was split into the following two groups, which are discussed below. This can be very helpful in . If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. And these two doses need to be separated by at least 7 days. Answer by DrLact: About Venofer usage in lactation. Venofer is used to treat iron deficiency anemia in people with kidney disease. There have also been reports of serious allergic reactions to Venofer. Mild side effects of Injectafer can include:*. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Data on file, American Regent, Inc. 1. Infusions should be administered over at least 15 minutes. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. The following information is provided for clinicians and other healthcare professionals. With IDA, you have low hemoglobin levels. What is Venofer? In Canada - Call your doctor for medical advice about side effects. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Call your doctor right away if you have serious side effects. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. For some people, it may be OK to continue taking a multivitamin that contains iron. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Wellbutrin: Side effects and how to manage them - Medical News Today Discuss the risks and benefits with your doctor. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. But if they become more severe or dont go away, talk with your doctor or pharmacist. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Any long-term side effects/dangers from iron infusions? Side effects like nausea and low blood pressure are common with most iron infusions. Many patients with kidney disease cannot get enough iron from food and require injections. Taking a higher dose than needed can often lead to adverse effects. Upset stomach or throwing up. Venofer infusions- how long does it take to notice improvement?? - Reddit To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Does Venofer Vial interact with other medications? If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. What is the latest research on the form of cancer Jimmy Carter has? I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Its not known if Injectafer is safe to use during pregnancy. This allows them to manage any side effects that you may have following your dose. Injectafer contains the active drug ferric carboxymaltose. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. PDF Protocol for the use of Intravenous Iron Sucrose (Venofer After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. Venofer (iron sucrose) Uses, Dosage, Side Effects - Drugs.com Youll receive doses of either drug by a healthcare professional at a medical facility. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. wAd**CgI%"nn{Oa[q{r5 In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Medically reviewed by Sanjai Sinha, MD. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. Always review your medical history with the treatingphysician. I can't take oral supplements because they cause horrible debilitating Constipation. Keep all drugs in a safe place. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Dizziness. Depending on your anemia symptoms, your weight changes may be different than those described here. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. However, consuming large amounts of alcohol can actually cause anemia in some people. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Do not double the dose to catch up. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Most people do not know how long theirside effectswill last until they go through them. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Iron infusions are given directly into a vein. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Mental healthdisorders like depression may requireantidepressantsto treat. Tell your doctor if you are pregnant or plan to become pregnant. You may report side effects to FDA at 1-800-FDA-1088. Phosphorus is an electrolyte that your body needs in order to make energy. 2. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. weakness. endobj And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Pain, swelling, or redness at the injection site may occur. Side effectswill last a very long time if the cause of them is not resolved. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. After the infusion, you can drive yourself home and return to your usual activities. (A medication class describes a group of drugs that work in the same way.). For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Theyll likely have you stop taking the pills while youre using Injectafer. How is Venofer (iron sucrose) given? Consult your pharmacist or local waste disposal company. Together, you and your doctor can develop a treatment plan thats best for you. You should not receive Venofer if you have known allergies to iron sucrose. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Dizziness. <> Cardiovascular health: Insomnia linked to greater risk of heart attack. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Check with your pharmacist if you have questions about the best way to throw out drugs. FG Trade/E+ sia Getty Images Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Venofer (Iron Sucrose (Injection)) - Side Effects, Interactions, Uses Call your doctor for medical advice about side effects. Source: Wolters Kluwer Health. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Injectafer begins working as soon as it enters your body. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. Your doctor will be able to see how Venofer is working by reviewing your blood tests. 2023 Medicine.com All rights reserved. Here are answers to some frequently asked questions about Injectafer. Many people using this medication do not have serious side effects. Which tests can diagnose iron deficiency anemia? SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Other drugs are available that can treat iron deficiency anemia (IDA). Iron Sucrose (Intravenous Route) Precautions - Mayo Clinic Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. It may also cause nervousness, restlessness, and difficulty sleeping in some people. Vomiting. Throw away unused or expired drugs. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. Be ready to tell or show what was taken, how much, and when it happened. Your doctor will go over your This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Once inside your body, ferric carboxymaltose releases iron into your system. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Learn how to store and discard medical supplies safely. You will be watched closely by your doctor for 30 minutes after each dose. Does Venofer Vial interact with other drugs you are taking? reese0809 1 yr. ago. For example: Say you weigh 105 pounds (about 48 kilograms). These are not all of the side effects that may occur. Consult the product instructions and your pharmacist for storage details. Injectafer helps to treat IDA by providing an iron infusion directly into your body. Pain in your limbs. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Iron infusion benefits. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. <> Injectafer should be stored between 68F to 77F (20C to 25C). Nausea. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Injectafer comes as a liquid solution inside vials. Injectafer infusions are given over a period of at least 15 minutes. A variety of tests can diagnose iron deficiency anemia. Venofer (iron sucrose): Basics, Side Effects & Reviews - GoodRx Patients with celiac disease (gluten intolerance). However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. This product may contain inactive ingredients, which can cause allergic reactions or other problems. If you have symptoms of a low phosphorus level, call your doctor. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Venofer is given as an infusion into a vein. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. (A generic drug is an exact copy of the active drug in a brand-name medication.). Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Venofer Side Effects. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Its not currently available in generic form. Others last much longer (even a lifetime), which can be quite traumatizing to people. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Before using, check this product visually for particles or discoloration. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. With IDA, you have low hemoglobin levels. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. The drug helps increase your hemoglobin level back to a value thats within the normal range. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
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